| J | Fecha | Local | Res. | Visitante | Hora | Nota | Lugar | |
| 13 | 3/23/2011 | Dep Savio | 0 - 0 | Olimpia | 17:30 | 0 | Sergio Reyes | |
| 13 | 3/23/2011 | Hispano | 2 - 0 | Necaxa | 19:00 | 0 | Carlos Miranda | |
| 13 | 3/23/2011 | Vida | 2 - 1 | Marathón | 19:00 | 0 | Ceibeño | |
| 13 | 3/23/2011 | Motagua | 1 - 1 | Platense | 19:30 | 0 | Nacional | |
| 13 | 3/23/2011 | Real España | 2 - 3 | Victoria | 19:30 | 0 | Francisco Morazán |