| J | Fecha | Local | Res. | Visitante | Hora | Nota | Lugar | |
| 2 | 1/22/2011 | Vida | 5 - 3 | Dep Savio | 19:30 | 0 | Ceibeño | |
| 2 | 1/23/2011 | Necaxa | 2 - 1 | Real España | 14:00 | 0 | Marcelo Tinoco | |
| 2 | 1/23/2011 | Hispano | 0 - 0 | Motagua | 15:00 | 0 | Carlos Miranda | |
| 2 | 1/23/2011 | Marathón | 0 - 1 | Platense | 15:00 | 0 | Yankel Rosenthal | |
| 2 | 1/23/2011 | Olimpia | 3 - 1 | Victoria | 16:00 | 0 | Nacional |